Sung-Hwan Park Selected Research

Arthritis (Polyarthritis)

11/2022	Methotrexate-loaded nanoparticles ameliorate experimental model of autoimmune arthritis by regulating the balance of interleukin-17-producing T cells and regulatory T cells.
1/2022	Vitronectin-derived bioactive peptide prevents spondyloarthritis by modulating Th17/Treg imbalance in mice with curdlan-induced spondyloarthritis.
1/2022	A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells.
12/2021	Retention rate and effectiveness of secukinumab vs TNF inhibitor in ankylosing spondylitis patients with prior TNF inhibitor exposure.
1/2021	Therapeutic Potential of a Novel Bifidobacterium Identified Through Microbiome Profiling of RA Patients With Different RF Levels.
12/2020	Combinatmarion treatment with Lactobacillus acidophilus LA-1, vitamin B, and curcumin ameliorates the progression of osteoarthritis by inhibiting the pro-inflammatory mediators.
10/2020	Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome.
1/2020	A bispecific soluble receptor fusion protein that targets TNF-α and IL-21 for synergistic therapy in inflammatory arthritis.
10/2019	Protein inhibitor of activated STAT3 reduces peripheral arthritis and gut inflammation and regulates the Th17/Treg cell imbalance via STAT3 signaling in a mouse model of spondyloarthritis.
1/2019	Suberoylanilide Hydroxamic Acid Attenuates Autoimmune Arthritis by Suppressing Th17 Cells through NR1D1 Inhibition.

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Sung-Hwan Park Research Topics

Disease

92	Rheumatoid Arthritis 10/2022 - 05/2002
74	Arthritis (Polyarthritis) 11/2022 - 04/2002
60	Inflammation (Inflammations) 01/2022 - 01/2004
52	Experimental Arthritis 01/2022 - 04/2002
28	Osteoarthritis 04/2022 - 01/2005
23	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2022 - 04/2002
21	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2005
20	Ankylosing Spondylitis 09/2022 - 02/2010
14	Neoplasms (Cancer) 01/2021 - 06/2003
12	Fibrosis (Cirrhosis) 01/2021 - 01/2005
9	Pain (Aches) 01/2021 - 02/2012
8	Colitis 01/2021 - 01/2016
7	Axial Spondyloarthritis 12/2021 - 10/2015
7	Proteinuria 01/2021 - 09/2005
7	Obesity 01/2021 - 06/2011
6	Lupus Nephritis 01/2022 - 01/2013
6	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2020 - 01/2013
6	Breast Neoplasms (Breast Cancer) 01/2020 - 06/2003
5	Necrosis 01/2017 - 08/2007
4	Sialadenitis 01/2022 - 01/2019
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2020
4	Sjogren's Syndrome (Sjogren Syndrome) 11/2019 - 03/2012
4	Systemic Scleroderma (Systemic Sclerosis) 09/2017 - 07/2003
4	Behcet Syndrome (Behcet's Syndrome) 08/2013 - 06/2002
3	Mitochondrial Diseases (Mitochondrial Disease) 04/2022 - 01/2017
3	Gout 01/2022 - 02/2015
3	Lymphadenopathy 01/2021 - 12/2005
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 03/2015
3	Dry Eye Syndromes (Dry Eye Syndrome) 06/2020 - 07/2014
3	Metabolic Bone Diseases (Osteopenia) 02/2017 - 06/2015
3	Infections 01/2017 - 01/2012

Drug/Important Bio-Agent (IBA)

42	CytokinesIBA 01/2022 - 07/2002
27	Interleukin-17 (Interleukin 17)IBA 12/2021 - 01/2005
22	Therapeutic UsesIBA 01/2022 - 06/2009
17	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 08/2006
16	InterleukinsIBA 01/2022 - 01/2005
14	AutoantibodiesIBA 01/2022 - 07/2012
13	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 05/2013
13	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2010
12	Biological ProductsIBA 09/2022 - 08/2006
12	Collagen Type II (Type II Collagen)IBA 01/2019 - 04/2002
11	Pharmaceutical PreparationsIBA 02/2022 - 01/2012
9	Antigen-Antibody Complex (Immune Complex)IBA 01/2021 - 05/2009
9	Immunoglobulin G (IgG)IBA 01/2020 - 04/2002
9	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2018 - 05/2006
8	interleukin-21 (interleukin 21)IBA 01/2021 - 01/2011
7	Tumor Necrosis Factor InhibitorsIBA 02/2022 - 11/2012
7	Interleukin-6 (Interleukin 6)IBA 01/2022 - 03/2012
7	Biomarkers (Surrogate Marker)IBA 12/2021 - 10/2011
7	CollagenIBA 01/2021 - 05/2013
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 07/2003
6	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 02/2015
5	Interleukin-10 (Interleukin 10)IBA 01/2020 - 01/2010
5	Etanercept (Enbrel)FDA Link 01/2019 - 02/2010
5	AntigensIBA 01/2017 - 03/2006
5	Interleukin-23 (Interleukin 23)IBA 10/2015 - 05/2006
4	Methotrexate (Mexate)FDA LinkGeneric 11/2022 - 12/2013
4	Adalimumab (Humira)FDA Link 05/2022 - 02/2010
4	coenzyme Q10 (CoQ10)IBA 01/2022 - 09/2017
4	C-Reactive ProteinIBA 12/2021 - 01/2014
4	Rheumatoid FactorIBA 11/2021 - 06/2013
4	rebamipideIBA 01/2021 - 01/2013
4	Infliximab (Remicade)FDA Link 01/2021 - 08/2007
4	Tacrolimus (Prograf)FDA LinkGeneric 01/2021 - 08/2013
4	Immunosuppressive Agents (Immunosuppressants)IBA 01/2021 - 05/2007
4	Iodoacetic AcidIBA 01/2021 - 01/2013
4	Uric Acid (Urate)IBA 11/2020 - 06/2015
4	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020 - 08/2006
4	Dextrans (Dextran)FDA Link 07/2019 - 01/2018
4	sodium sulfate (sodium bisulfate)FDA LinkGeneric 07/2019 - 01/2018
4	Interleukin-1 (Interleukin 1)IBA 01/2018 - 08/2006
4	Interleukin-8 (Interleukin 8)IBA 01/2018 - 02/2007
4	AntioxidantsIBA 09/2017 - 06/2009
4	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2016 - 04/2008
4	NF-kappa B (NF-kB)IBA 03/2012 - 01/2005
4	Interleukin-15 (Interleukin 15)IBA 09/2011 - 05/2004
4	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2007 - 05/2002
3	amsonic acid (DAS)IBA 10/2022 - 03/2015
3	Biosimilar PharmaceuticalsIBA 05/2022 - 01/2019
3	LipidsIBA 08/2021 - 01/2020
3	Abatacept (Orencia)FDA Link 08/2021 - 03/2010
3	Antirheumatic Agents (DMARD)IBA 08/2021 - 12/2019
3	InterferonsIBA 01/2021 - 01/2008
3	Celecoxib (Celebrex)FDA Link 01/2021 - 01/2013
3	Interferon Type IIBA 01/2021 - 06/2015
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2017
3	AntibodiesIBA 11/2020 - 04/2002
3	DNA (Deoxyribonucleic Acid)IBA 11/2020 - 01/2003
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 04/2019 - 02/2012
3	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2019 - 01/2016
3	ZincIBA 04/2018 - 01/2018
3	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 05/2017 - 10/2012
3	Interleukin-33IBA 02/2015 - 09/2011
3	LigandsIBA 04/2013 - 04/2008
3	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 07/2012 - 01/2008
3	proanthocyanidinIBA 01/2012 - 06/2009

Therapy/Procedure

28	Therapeutics 01/2022 - 09/2005
5	Oral Administration 01/2021 - 04/2008
3	Synchrotrons 01/2019 - 10/2012
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2016 - 08/2012